• Costa B, Li Calzi M, Castellano M, Blanco V, Cuevasanta E, Litvan I, Ivanov P, Witwer K, Cayota A, Tosar J.P.* (2023). Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids. P.N.A.S. 120(4) e2216330120. DOI. PubMed

Comment in: Staying together after the breakup: tRNA halves in extracellular fluids

• Tosar JP*, Cayota A, Witwer K (2022). Exomeres and Supermeres: monolithic or diverse? Journal of Extracellular Biology. DOI. PubMed

• Mateescu B, Jones J, Alexander R, et al. (2022). Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research. iScience. DOI. PubMed

• Marquez ME, Sernbo S, Payque E, Uria R, Tosar JP, Querol J, Berca C, Uriepero A, Prieto D, Álvarez D,  Oliver C, Irigoin V, Dos Santos G, Guillermo C, Landoni AI, Navarrete M, Palacios F, Oppezzo P (2022). TGF-β/SMAD Pathway Is Modulated by miR-26b-5p: Another Piece in the Puzzle of Chronic Lymphocytic Leukemia Progression. Cancers 14 (7), 1676. DOI. 

• Alexander RP, Kitchen RR, Tosar JP, Roth M, Mestdagh P, Max KEA, Rozowsky J, Kaczor-Urbanowicz KE, Chang J, Balaj L, Losic B, Van Nostrand EL, LaPlante E, Mateescu B, White BS, Yu R, Milosavljevic A, Stolovitzky G, Spengler RM. (2022) Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop. Frontiers in Genetics 12:778416. DOI. PubMed.

• Fagúndez P, Botasini S, Tosar JP, Méndez E (2021) Systematic process evaluation of the conjugation of proteins to gold nanoparticles. Heliyon 7 (6): e07392. DOI. PubMed.

• Tosar JP, Ivanov P, Ribas de Pouplana L, Torres AG (2021) Editorial: Understanding the Importance of Non-Canonical tRNA Function. Frontiers in Molecular Biosciences 8: 769784. DOI. PubMed.

• Tosar JP* (2021) Die hard: resilient RNAs in the blood. Nature Reviews Molecular Cell Biology 22(6):373.  DOI. PubMed

• Tosar JP*, Gámbaro F, Castellano M, Cayota A (2021) RI-SEC-seq: Comprehensive Profiling of Nonvesicular Extracellular RNAs with Different Stabilities. Bio-protocol 11(4): e3918. DOI. PubMed

• Arab T,  Mallick E, Huang Y, Dong L, Liao Z, Zhao Z, Gololobova O, Smith B, Haughey N, Pienta K, Slusher B, Tarwater P, Tosar JP, Zivkovic A, Vreeland W, Paulaitis M, Witwer KW (2021) Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms. Journal of Extracellular Vesicles 10(6): e12079. DOI. PubMed

• Tosar JP*, Witwer KW, Cayota A (2021) Revisiting Extracellular RNA Release, Processing, and Function. Trends in Biochemical Sciences 46(6): 438-445. DOI. PubMed

• Tosar JP*, García-Silva MR, Cayota A (2021) Circulating SNORD57 rather than piR-54265 is a promising biomarker for colorectal cancer: common pitfalls in the study of somatic piRNAs in cancer. RNA 27(4): 403-410. DOI. PubMed 

• Tosar JP*, Segovia M, Castellano M, Gámbaro F, Akiyama Y, Fagúndez P, Olivera A, Costa B, Possi T, Hill M, Ivanov P, Cayota A* (2020) Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome. Nucleic Acids Research 48(22): 12874-12888, DOI. PubMed 

• Tosar JP*, Cayota A* (2020) Extracellular tRNAs and tRNA-derived fragments. RNA Biology 17(8): 1149 - 1167. DOI. PubMed

• Fagúndez P, Brañas G, Laíz J, Tosar JP.* (2020) Electrochemical Detection of dsDNA-Specific Antibodies. Methods in Molecular Biology 2063: 73-83, DOI. PubMed

• Gámbaro F, Li Calzi M, Fagúndez P, Costa B, Greif G, Mallick E, Lyons S, Ivanov P, Witwer K, Cayota A*, Tosar JP.* (2020) Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner. RNA Biology 17(8): 1168 - 1182.  DOI. PubMed

• Fernández-Calero T, Davyt M, Perelmuter K, Chalar C, Bampi G, Persson H, Tosar JP, Hafstao V, Naya H, Rovira C, Bollati-Fogolin M, Ehrlich R, Flouriot G, Ignatova Z, Marín M (2020) Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells. Cancer & Metabolism 8, 8. DOI. PubMed. 

• Fromm B, Tosar JP, Aguilera F, Friedländer MR, Bachmann L, Hejnol A (2019) Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha). Non-Coding RNA  5, e19. DOI. PubMed 

• Fromm B, Kang W, Rovira C, Cayota A, Witwer KW*, Friedländer M*, Tosar JP* (2019) Plant microRNAs in human sera are likely contaminants. Journal of Nutritional Biochemistry 65: 139-140. DOI. PubMed

• Théry C, Witwer K, et al. (2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles 7 (1), e1535750. DOI. PubMed

• Tosar JP,*; Gámbaro F, Darré L, Pantano S, Westhof E, Cayota A* (2018) Dimerization confers increased stability to nucleases in extracellular 5’ halves from glycine and glutamic acid tRNAs. Nucleic Acids Research 46 (17), 9081-9093. DOI. PubMed

• Fromm B, Tosar JP, Yu L, Halushka M, Witwer K (2018). Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk. Journal of Nutrition, 148 (9), 1506-1507. DOI. PubMed

• Tosar JP, Cayota A (2018) Detection and analysis of non-vesicular extracellular RNA. Methods in Molecular Biology 1740: 125-137. DOI. PubMed

• Fagúndez P, Brañas G, Cairoli E, Laíz J, Tosar JP* (2018). An electrochemical biosensor for rapid detection of anti-dsDNA antibodies in absolute scale. Analyst  143:3874-3882. DOI. PubMed

• Tosar JP*, Rovira C, Cayota A (2018) Non-coding RNA fragments account for the majority of annotated piRNAs expressed in somatic non-gonadal tissues.  Communications Biology 1, e2. DOI. PubMed

• Tosar JP, Cayota A, Eitan E, Halushka MK, Witwer KW (2017) Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components? Journal of Extracellular Vesicles 6 (1), e1272832. DOI. PubMed

• Mateescu B, Kowal EJK, van Balkom BWM, et al. (2017) Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper. Journal of Extracellular Vesicles 6 (1), e1286095. DOI. PubMed 

•  Doldán X, Fagúndez P, Cayota A, Laíz J, Tosar JP* (2016) Electrochemical sandwich immunosensor for determination of exosomes based on surface marker-mediated signal amplification. Analytical Chemistry 88 (21): 10466-10473. DOI. PubMed

• Tosar JP, Gámbaro F, Sanguinetti J, Bonilla B, Witwer KW, Cayota A (2015) Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines. Nucleic Acids Research 43 (11): 5601-5616. DOI. PubMed

• Tosar, J.P.; Rovira, C.; Naya, H.; Cayota, A. (2014) Mining of public sequencing datasets supports a non-dietary origin for putative foreign miRNAs: underestimated effects of contamination in NGS. RNA 20 (6): 754-757. DOI. PubMed

• Tosar JP, Holmes J, Collyer S, Davis F, Laíz J,* Higson H (2013) Template and catalytic effects of DNA in the construction of polypyrrole/DNA composite macro and microelectrodes. Biosensors & Bioelectronics, 41: 294-301.  DOI. PubMed

• García-Silva M.R.1; Tosar, J.P1.; Frugier, M.; Pantano, S.; Bonilla, B.; Esteban, L.; Serra, E.; Rovira, C.; Robello, C.; Cayota, A. (2010) Cloning, characterization and subcellular localization of a trypanosoma cruzi argonaute protein defining a new subfamily distinctive of trypanosomatids . Gene 466: 26 - 35. DOI. PubMed

• García-Silva M.R.; Frugier, M.; Tosar, J.P.; Correa Dominguez, A.; Ronalte Alvez, L.; Parodi-Talice, A.; Rovira, C.; Robello, C.; Goldenberg, S.; Cayota, A (2010) A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to cytoplasmic granules. Molecular and Biochemical Parasitology 171 (2): 64 – 73. DOI. PubMed

• Tosar JP, Brañas G, Laíz J* (2010). Electrochemical DNA hybridization sensors applied to real and complex biological samples. Biosensors & Bioelectronics 26 (4): 1205-1217. DOI. PubMed

• Tosar JP, Keel K, Laíz J* (2009) Two independent label-free detection methods in one electrochemical DNA sensor. Biosensors & Bioelectronics 24 (10): 3036 – 3042. DOI. PubMed